Duke vs. Florida State odds, line, spread: Computer model reveals college football picks and predictions for Week 8, 2024

The Florida State Seminoles (1-5, 1-1) will face the Duke Blue Devils (5-1, 1-1) in an ACC matchup on Friday. Kickoff at Wallace Wade Stadium in Durham, North Carolina is scheduled for 7:00 p.m. ET. The Seminoles are coming off a bye and are trying to end a two-game losing streak, losing 29-13 to Clemson in their last game. Duke, coming off its own bye, will look to bounce back from its 24-14 loss to Georgia Tech.

The Blue Devils are the SportsLine consensus 3-point favorites in the current Florida State vs. Duke odds, while the over/under for total points scored is 42.5. Duke is a moneyline favorite at -150 (risking $150 to win $100), while Florida State is listed as a +125 underdog.

Before making any Duke vs. Florida State picks or CFB predictions, you need to see what the SportsLine projection model has to say.

The model simulates every FBS college football game 10,000 times. Since its inception, its top-rated college football picks against the spread have generated well over $2,000 in profits for $100 players. It's also a sizzle 12-5 with top-rated picks in the final three weeks of this season. Everyone who has followed it has seen STRONG returns!

The model knows that the Noles have a perfect 22-0 all-time record against the Blue Devils, but that they need to play better than they have in recent weeks. The Seminoles are still playing without quarterback DJ Uiagalelei (hand), who was injured in a 42-16 loss to SMU. Freshman Brock Glenn had a solid performance in his absence, completing 23 of 41 passes for 228 yards with two touchdowns and an interception against Clemson.

The model also knows that the Blue Devils' defense was among the best in the conference this season, leading the ACC in total yards allowed per game (309.3) and points allowed per game (17.5). ranked second, while linebacker Alex Howard led the Dukes' defense with 47 total tackles. Sophomore quarterback Maalik Murphy has thrown for 1,431 yards with 14 touchdowns and five interceptions, while star running back Thomas has thrown for 528 yards with 113 carries and three touchdowns.

The model has simulated Duke vs. Florida State 10,000 times and the results are in. We can tell you that the model is trending in terms of the total, and it also says that one side of the range applies more than 50% of the time!

Who wins Florida State vs. Duke, And which side of the spread applies more than 50% of the time? … Join SportsLine now to find out which side of the spread you should be on from the model that's 12-5 on top-rated CFB picks over the last three weeks!